LION'S MANE MUSHROOM: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews (2024)

Overview

Lion's mane (Hericium erinaceus) is a mushroom that grows on trunks of dead hardwood trees such as oak. It has a long history of use in East Asian medicine.

Lion's mane mushroom might improve nerve development and function. It might also protect nerves from becoming damaged. It also seems to help protect the lining in the stomach.

People use lion's mane mushroom for Alzheimer disease, dementia, stomach problems, and many other conditions, but there is no good scientific evidence to support these uses. There is also no good evidence to support using lion's mane mushroom for COVID-19.

Uses & Effectiveness ?

We currently have no information for LION'S MANE MUSHROOM overview.

Side Effects

When taken by mouth: Lion's mane mushroom is possibly safe when used in a dose of 1 gram daily for 16 weeks. Side effects are mild and may include stomach discomfort.

When applied to the skin: There isn't enough reliable information to know if lion's mane mushroom is safe when applied to the skin or what the side effects might be.

Special Precautions and Warnings

When taken by mouth: Lion's mane mushroom is possibly safe when used in a dose of 1 gram daily for 16 weeks. Side effects are mild and may include stomach discomfort.

When applied to the skin: There isn't enough reliable information to know if lion's mane mushroom is safe when applied to the skin or what the side effects might be.

Pregnancy and breast-feeding: There isn't enough reliable information to know if lion's mane mushroom is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Auto-immune diseases such as multiple sclerosis (MS), lupus (systemic lupus erythematosus, SLE), rheumatoid arthritis (RA), pemphigus vulgaris (a skin condition), and others: Lion's mane mushroom might cause the immune system to become more active, and this could increase the symptoms of auto-immune diseases. If you have one of these conditions, it's best to avoid using lion's mane mushroom.

Bleeding conditions: Lion's mane mushroom might slow blood clotting. This might increase the chances of bruising and bleeding in people with bleeding conditions.

Surgery: Lion's mane mushroom might slow blood clotting and reduce blood glucose levels. This might cause extra bleeding, and interfere with blood sugar control during and after surgery. Stop using lion's mane mushroom at least 2 weeks before a scheduled surgery.

Interactions ?

    Moderate Interaction

    Be cautious with this combination

  • Medications for diabetes (Antidiabetes drugs) interacts with LION'S MANE MUSHROOM

    Lion's mane mushroom might lower blood sugar levels. Taking lion's mane mushroom along with diabetes medications might cause blood sugar to drop too low. Monitor your blood sugar closely.

  • Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with LION'S MANE MUSHROOM

    Lion's mane mushroom might slow blood clotting. Taking lion's mane mushroom along with medications that also slow blood clotting might increase the risk of bruising and bleeding.

  • Medications that decrease the immune system (Immunosuppressants) interacts with LION'S MANE MUSHROOM

    Lion's mane mushroom can increase the activity of the immune system. Some medications, such as those used after a transplant, decrease the activity of the immune system. Taking lion's mane mushroom along with these medications might decrease the effects of these medications.

Dosing

There isn't enough reliable information to know what an appropriate dose of lion's mane mushroom might be. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.

Next

  • Common Searches:
  • Alpha Lipoic Acid
  • Apple Cider Vinegar
  • Black Cohosh
  • Calcium
  • Chromium
  • Coenzyme Q - 10
  • DHEA
  • Flaxseed
  • Folic Acid
  • Ginko
  • Glucosamine
  • Melatonin
  • Niacin
  • Magnesium
  • Probiotics
  • Red Yeast Rice
  • St. John's Wort
  • Vitamin C
  • Vitamin D
  • Vitamin E

Show More Show Less

CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circ*mstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
© Therapeutic Research Faculty 2020.

LION'S MANE MUSHROOM: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews (2024)

FAQs

Who should avoid lion's mane? ›

Lion's mane may also slow blood clotting and blood sugar levels. For this reason, it may interact with blood-clotting medications and diabetes treatments, Richard says. Don't consume lion's mane if you're allergic or sensitive to mushrooms.

Are there any side effects to taking Lion's Mane? ›

There have been documented cases of people experiencing difficulty breathing or skin rashes after exposure to lion's mane mushrooms, likely related to allergies ( 63 , 64 ). Animal studies suggest that lion's mane mushroom and its extracts are very safe, even at high doses.

Is lions mane mushroom bad for your liver? ›

Lion's mane is generally recognized as safe and has not been linked to serum enzyme elevations during therapy nor to episodes of clinically apparent liver injury.

Can lions mane mushroom raise blood pressure? ›

Those studies showed that lion's mane can help regulate blood sugar and reduce high blood pressure, as well as other mental and brain health applications including treating depression and improving recovery after a traumatic brain injury, according to an article in Popular Science.

What can you not mix with Lion's Mane? ›

Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with LION'S MANE MUSHROOM. Lion's mane mushroom might slow blood clotting. Taking lion's mane mushroom along with medications that also slow blood clotting might increase the risk of bruising and bleeding.

Is Lion's Mane FDA approved? ›

Is lion's mane mushroom a drug? Lion's mane mushroom is not a drug. It's available as a food or a dietary supplement. Any health claims on dietary supplements have not been reviewed by the FDA.

Is Lion's Mane addictive? ›

Furthermore, Lion's Mane does not contain any addictive substances such as opioids or psychoactive compounds. It is primarily composed of bioactive compounds, including polysaccharides and hericenones, which are believed to contribute to its potential health benefits.

How quickly does lion's mane work? ›

Does lion's mane work immediately? While some people may feel a difference incredibly quickly after only a few days, this is rare. Most users will need to take lion's mane regularly for several weeks or 2-3 months before feeling a significant effect and reaping the long-term benefits.

Does lion's mane affect the immune system? ›

Lion's Mane has been shown to support normal immunity by increasing the activity of the intestinal immune system. Lion's Mane contains a special type of polysaccharide called beta-glucan, which is well known to support the activity of innate immune cells.

Is Lion's Mane bad for your heart? ›

Research suggests that Lion's mane mushrooms may offer a range of health benefits, including reduced inflammation and improved cognitive and heart health. People can eat them or take them in the form of supplements. Lion's mane mushrooms (Hericium erinaceus) are white, globe-shaped fungi that have long, shaggy spines.

Can mushroom supplements cause liver damage? ›

The Susan G. Komen Foundation note that reishi mushroom extract is possibly safe for up to 1 year when a person takes it orally. However, they also note that taking powdered reishi mushroom for longer than 1 month may be toxic to the liver.

Is Lion's Mane bad for your kidneys? ›

Lion's Mane is another type of mushroom known for its numerous health benefits, including potential kidney benefits. While further studies are needed to understand its full impact on kidney health, initial research, and traditional usage suggest it may have protective effects on the kidneys.

Can lion's mane cause blood clots? ›

Bleeding Disorders: Lion's Mane has been shown to have blood thinning properties. If you have a bleeding disorder and take blood thinner (anticoagulant/antiplatelet) medication, you should avoid taking Lion's Mane mushroom supplements, as it may slow down blood clotting or cause bruising.

What happens if you take lion's mane every day? ›

A more recent study, published in June 2020 in Frontiers in Aging Neuroscience, found that taking three 350 mg capsules of lion's mane daily for 49 weeks may have helped lead to significant improvements in brain health in people with mild Alzheimer's disease.

Does Lion's Mane have side effects? ›

“Lion's mane is generally well tolerated, but the most common side effects include gastrointestinal discomfort, nausea and a skin rash,” says Dr. Watson. If you experience side effects, discontinue lion's mane consumption until you've spoken with a health care provider.

Is Lion's Mane good for seniors? ›

The human research we do have shows there may be a possible benefit of lion's mane supplements in older adults with mild cognitive impairment or Alzheimer's disease. But larger studies are needed to confirm this. Mushrooms like lion's mane are nutrient-rich and can be eaten as part of a balanced diet.

Can lion's mane increase heart rate? ›

17 Hypoglycemia (low blood sugar) could result, especially if lion's mane is taken with diabetes medicines. Watch for signs of hypoglycemia, like shakiness, headache, or a fast heart rate. Blood thinners: One of lion's mane's components slows blood clotting.

Is lion's mane bad for kidneys? ›

Lion's Mane is another type of mushroom known for its numerous health benefits, including potential kidney benefits. While further studies are needed to understand its full impact on kidney health, initial research, and traditional usage suggest it may have protective effects on the kidneys.

Should I take Ashwagandha or lions mane? ›

If you're dealing with chronic stress, sleep disturbances, or general well-being, Ashwagandha may be your best bet. On the other hand, if you're looking to boost cognitive function, memory, and mood, Lion's Mane might be the more suitable option.

Top Articles
Latest Posts
Article information

Author: Edmund Hettinger DC

Last Updated:

Views: 6185

Rating: 4.8 / 5 (78 voted)

Reviews: 93% of readers found this page helpful

Author information

Name: Edmund Hettinger DC

Birthday: 1994-08-17

Address: 2033 Gerhold Pine, Port Jocelyn, VA 12101-5654

Phone: +8524399971620

Job: Central Manufacturing Supervisor

Hobby: Jogging, Metalworking, Tai chi, Shopping, Puzzles, Rock climbing, Crocheting

Introduction: My name is Edmund Hettinger DC, I am a adventurous, colorful, gifted, determined, precious, open, colorful person who loves writing and wants to share my knowledge and understanding with you.